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Evaluation of antigen-detecting and antibody-detecting diagnostic test combinations for diagnosing melioidosis.

Premjit AmornchaiViriya HantrakunGumphol WongsuvanVanaporn WuthiekanunSurasakdi WongratanacheewinPrapit TeparrakkulTimothy Eoin WestDavid P AuCoinNicholas Philip John DayPaul J BrettMary N BurtnickNarisara ChantratitraDirek Limmathurotsakul
Published in: PLoS neglected tropical diseases (2021)
A combination of antigen-antibody diagnostic tests increased the sensitivity of melioidosis diagnosis over individual tests while preserving high specificity. Point-of-care tests for melioidosis based on the use of combination assays should be further developed and evaluated.
Keyphrases
  • single cell
  • structural basis