Systematically Exploring the Antitumor Mechanisms of Core Chinese Herbs on Hepatocellular Carcinoma: A Computational Study.

Zhulin WuLi HeLianan WangLi-Sheng Peng

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

By combining data mining, network pharmacology, molecular docking, and survival analysis methods, we found that CCHs may play a therapeutic role in HCC through regulating the target genes and pathways related to cancer occurrence and development, angiogenesis, metastasis, and prognosis.

Keyphrases

molecular docking
molecular dynamics simulations
papillary thyroid
risk assessment
genome wide
electronic health record
squamous cell
big data
squamous cell carcinoma
dna methylation
machine learning
deep learning
transcription factor
bioinformatics analysis