Renomedullary Interstitial Cell Endothelin A Receptors Regulate BP and Renal Function.
Chunyan HuJayalakshmi LakshmipathiDeborah StuartJános Peti-PeterdiGeorgina GyarmatiChuan-Ming HaoPeter HansellDonald E KohanPublished in: Journal of the American Society of Nephrology : JASN (2020)
Disruption of renomedullary interstitial cell endothelin A receptors reduces BP and increases salt and water excretion associated with enhanced production of intrinsic renal natriuretic and diuretic factors. These studies indicate that renomedullary interstitial cells can modulate BP and renal function under physiologic conditions.