New Insights into the Impact of Human Papillomavirus on Oral Cancer in Young Patients: Proteomic Approach Reveals a Novel Role for S100A8.
Marisol M GalvisCarolina Carneiro SoaresCarolina Moretto CarnieliJaqueline Ramalho ButturaRaisa Sales de SáEstela KaminagakuraFabio Albuquerque MarchiAdriana Franco Paes LemeClóvis A Lópes PintoAlan Roger Santos-SilvaRogerio de Moraes CastilhoLuiz Paulo KowalskiCristiane Helena SquarizePublished in: Cells (2023)
HPV (+) OSCC has a peculiar microenvironment pattern distinctive from HPV (-), involving the expression of pathogen-associated pattern receptors, S100A8 overexpression, and NFκB activation and responses, which has important consequences in prognosis and may guide therapeutic decisions.