Sentinel lymph node detection in oral cancer: a within-patient comparison between [99mTc]Tc-tilmanocept and [99mTc]Tc-nanocolloid.
Inne J den ToomRutger MahieuRob van RooijRobert J J van EsMonique G G HobbelinkGerard C KrijgerBernard M TijinkBart de KeizerRemco de BreePublished in: European journal of nuclear medicine and molecular imaging (2020)
[99mTc]Tc-tilmanocept had a higher injection site clearance, but at the same time a lower uptake in the SLN, resulting in an SLN to injection site ratio, which was not significantly different from [99mTc]Tc-nanocolloid. The relatively low-radioactive uptake in SLNs of [99mTc]Tc-tilmanocept may limit intraoperative detection of SLNs, but can be overcome by a higher injection dose.