Development of a multiplex Loop-Mediated Isothermal Amplification (LAMP) for the diagnosis of bacterial periprosthetic joint infection.

Woong Sik JangSeoyeon ParkJi Hoon BaeSoo Young YoonChae Seung LimMin-Chul Cho

Published in: PloS one (2024)

This multiplex LAMP assay can rapidly detect five high-prevalence bacterial species causing bacterial PJI, with excellent sensitivity and specificity, in less than 1 h, and it may be useful for the early diagnosis of PJI.

Keyphrases

loop mediated isothermal amplification
high throughput
sensitive detection
risk factors
real time pcr
total hip
total knee arthroplasty
total hip arthroplasty
single cell