Potential interactions among single nucleotide polymorphisms in bone- and cartilage-related genes in skeletal malocclusions.
Erika Calvano KüchlerCaio Luiz Bittecourt ReisJulia CarelliRafaela ScariotPaulo Nelson-FilhoRicardo Della ColettaAleysson Olimpio PazaMírian Aiko Nakane MatsumotoPeter ProffChristian KirschneckPublished in: Orthodontics & craniofacial research (2020)
Our results suggest that SNPs in BMP2, BMP4, SMAD6, RUNX2, WNT3A and WNT11 could be involved in the aetiology of sagittal and vertical malocclusions.
Keyphrases
- bone regeneration
- mesenchymal stem cells
- cell proliferation
- stem cells
- epithelial mesenchymal transition
- genome wide
- bone mineral density
- transcription factor
- transforming growth factor
- extracellular matrix
- human health
- gene expression
- risk assessment
- bone marrow
- dna methylation
- postmenopausal women
- bone loss
- genome wide association