A novel screening method of DNA methylation biomarkers helps to improve the detection of colorectal cancer and precancerous lesions.

Yuan LiBin LiRou JiangLe-En LiaoChunting ZhengJie YuanLiuhong ZengKunling HuYuyu ZhangWeijian MeiZhigang HongBin-Yi XiaoLingheng KongKai HanJinghua TangWu JiangZhizhong PanShenyan ZhangPeirong Ding

Published in: Cancer medicine (2023)

The combined detection of the methylation status of SEPT9, SDC2, and ALX4 in plasma holds the potential to further enhance the sensitivity of CRC detection.

Keyphrases

dna methylation
loop mediated isothermal amplification
label free
real time pcr
genome wide
gene expression
risk assessment
human health
copy number
sensitive detection
quantum dots