Maternal breast cancer risk in relation to birthweight and gestation of her offspring.

Anthony J SwerdlowLauren B WrightMinouk J SchoemakerMichael E Jones

Published in: Breast cancer research : BCR (2018)

Our data add to evidence that short gestation pregnancies may increase the risk of breast cancer, at least pre-menopausally, perhaps by hormonal stimulation and breast proliferation early in pregnancy without the opportunity for the differentiation that occurs in late pregnancy. High birthweight first pregnancies may increase breast cancer risk, possibly through the association of birthweight with oestrogen and insulin-like growth factor 1 levels.

Keyphrases

gestational age
breast cancer risk
preterm birth
birth weight
pregnancy outcomes
signaling pathway
high fat diet
pregnant women
type diabetes
metabolic syndrome
growth hormone
skeletal muscle
weight loss
data analysis
machine learning