Muscarinic inhibition of salivary glands with glycopyrronium bromide does not reduce the uptake of PSMA-ligands or radioiodine.
V MohanN M BruinM E T TesselaarJ P de BoerE VegtJ J M A HendrikxA Al-MamganiJ B van de KamerJ-J SonkeWouter V VogelPublished in: EJNMMI research (2021)
Muscarinic inhibition of salivation with GPB did not significantly reduce the uptake of PSMA-ligands or radioiodine in salivary glands, and can be dismissed as a potential strategy to reduce toxicity from radionuclide therapies.