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γ-Aminobutyric acid type A receptor binding affinity in the right inferior frontal gyrus at resting state predicts the performance of healthy elderly people in the visual sustained attention test.

Masato KasagiTomokazu MotegiKosuke NaritaKazuyuki FujiharaYusuke SuzukiMinami TagawaKoichi UjitaHirotaka ShimadaMasato Fukuda
Published in: International psychogeriatrics (2018)
The findings of 123I-IMZ SPECT, but not those of structural MRI or ASL, suggest that a decreased GABAA receptor binding affinity can be a sensitive marker of cognitive impairment.
Keyphrases
  • functional connectivity
  • resting state
  • cognitive impairment
  • binding protein
  • working memory
  • magnetic resonance imaging
  • pet ct
  • capillary electrophoresis
  • mass spectrometry