Association between Paraoxonase/Arylesterase Activity of Serum PON-1 Enzyme and Rheumatoid Arthritis: A Systematic Review and Meta-Analysis.

Gian Luca ErreStefania BassuRoberta GiordoArduino Aleksander Mangoni Ciriaco Carru Gianfranco Pintus Angelo Zinellu

Published in: Antioxidants (Basel, Switzerland) (2022)

Our meta-analysis has shown that both serum PON-1 and ARE activity are significantly lower in RA patients, suggesting a deficit in antioxidant defense mechanisms in this disease.

Keyphrases

rheumatoid arthritis
systematic review
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
oxidative stress
peritoneal dialysis
interstitial lung disease
meta analyses
patient reported outcomes
systemic sclerosis