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A combination of genomics and transcriptomics provides insights into the distribution and differential mRNA expression of type VI secretion system in clinical Klebsiella pneumoniae .

Wanzhen LiXiaolan HuangDan LiXiao-Fen LiuXiaoying JiangXingchen BianXin Li
Published in: mSphere (2024)
. This study also described the overall transcriptional changes in the predominant Chinese ST11 strain HS11286 upon deletion of crucial T6SS genes. Additionally, this work provides a reference for future research on the identification of T6SS in bacteria.
Keyphrases
  • klebsiella pneumoniae
  • single cell
  • multidrug resistant
  • escherichia coli
  • bioinformatics analysis
  • gene expression
  • genome wide
  • transcription factor
  • genome wide analysis