Direct Stimulatory Effects of the CB2 Ligand JTE 907 in Human and Mouse Islets.

Inmaculada Ruz-MaldonadoPatricio AtanesGuo Cai HuangBo LiuShanta J Persaud

Published in: Cells (2021)

Our observations show for the first time that JTE 907 acts as a Gq-coupled agonist in islets to stimulate insulin secretion and maintain β-cell mass in a GPR55-independent fashion.

Keyphrases

endothelial cells
single cell
cell therapy
induced pluripotent stem cells