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Metronidazole-induced encephalopathy.

Vikash G LalaBilal BobatMark HaagensenPrakash KathanAdam Mahomed
Published in: SA journal of radiology (2021)
Metronidazole is a widely used antibacterial and antiprotozoal agent for a number of conditions. Whilst its more common gastrointestinal side effects are well known, neurotoxicity remains under-recognised. Both central and peripheral neurological side effects have been described. This report describes a case of radiologically confirmed metronidazole-induced cerebellar ataxia in a cirrhotic patient with a review of the literature. Awareness of this side effect is essential for prompt recognition as early drug withdrawal leads to resolution in the majority of cases.
Keyphrases
  • high glucose
  • diabetic rats
  • drug induced
  • early onset
  • oxidative stress
  • case report
  • endothelial cells
  • cerebral ischemia
  • wound healing