Efficacy and safety of therapeutic strategies for human brucellosis: A systematic review and network meta-analysis.

Sarah Nascimento SilvaGláucia CotaDiego Mendes XavierGlaciele Maria de SouzaMarina Rocha Fonseca SouzaMoisés Willian Aparecido GonçalvesFelipe Francisco TuonEndi Lanza Galvão

Published in: PLoS neglected tropical diseases (2024)

This review confirmed the superiority of drugs already indicated for treating human brucellosis, such as the combination of doxycycline and aminoglycosides. The association of hydroxychloroquine to the dual regimen was identified as a potential strategy to prevent overall therapy failure, which is subject to confirmation in future studies.

Keyphrases

endothelial cells
stem cells
current status
risk assessment
mesenchymal stem cells