Sensitivity of quantitative relaxometry and susceptibility mapping to microscopic iron distribution.
Timothy J ColganGesine KnoblochScott B ReederDiego HernandoPublished in: Magnetic resonance in medicine (2019)
R 2 and R 2 * for iron quantification depend on the spatial distribution or iron. QSM-based estimation of iron concentration is insensitive to the microscopic spatial distribution of iron, potentially providing a distribution independent measure of iron concentration.