Immunofluorescence mapping, electron microscopy and genetics in the diagnosis and sub-classification of inherited epidermolysis bullosa: a single-centre retrospective comparative study of 87 cases with long-term follow-up.

Sabrina RossiD CastigliaE PisaneschiAndrea DiociaiutiA StracuzziC CesarioR MarianiG FloriddiaG ZambrunoR BoldriniD AbeniA NovelliR AlaggioM El Hachem

Published in: Journal of the European Academy of Dermatology and Venereology : JEADV (2021)

Transmission electron microscopy remains relevant to the diagnosis of EBS. IFM and genetics are essential and complementary tools in the vast majority of EB cases.

Keyphrases

electron microscopy
machine learning
high resolution
deep learning
mass spectrometry
high density