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Different clinical outcomes between cerebral amyloid angiopathy-related inflammation and non-inflammatory form.

Lou GrangeonG QuesneyM Verdalle-CazesS CouletteD RenardA WacongneT AllouN OlivierY BoukricheG Blanchet-FourcadeP LabaugeC ArquizanS CanapleO GodefroyO MartinaudP VerdureM Quillard-MuraineJ ParienteE MagninG NicolasC CharbonnierD MaltêteM FormaglioN RaposoX AyrignacD Wallon
Published in: Journal of neurology (2022)
CAA-ri appears to be more severe than non-inflammatory CAA with a significant loss of autonomy and global higher amyloid burden, shown by more CMB and a distinct CSF profile. This burden may be partially promoted by ε4 allele.
Keyphrases
  • oxidative stress
  • subarachnoid hemorrhage
  • cerebral ischemia
  • blood brain barrier