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Elevated Urinary Rab10 Phosphorylation in Idiopathic Parkinson Disease.

Shijie WangShakthi UnnithanNicole BryantAllison ChangLiana S RosenthalAlexander Y PantelyatTed M DawsonHussein R Al-KhalidiAndrew B West
Published in: Movement disorders : official journal of the Movement Disorder Society (2022)
These results provide initial insights into peripheral LRRK2-dependent Rab phosphorylation, measured in biobanked urine, where higher levels of pT73-Rab10 are associated with worse disease progression. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson Movement Disorder Society.
Keyphrases
  • parkinson disease
  • deep brain stimulation
  • protein kinase
  • systematic review