Quercetin-3-O-Glucuronide Alleviates Cognitive Deficit and Toxicity in Aβ1-42 -Induced AD-Like Mice and SH-SY5Y Cells.

Mengdai XuHao HuangXiaoxing MoYalun ZhuXi ChenXiaoqin LiXiaobo PengZihui XuLiangkai ChenShuang RongWei YangShuang LiuLiegang Liu

Published in: Molecular nutrition & food research (2021)

Q3G can alleviate brain IR through directly acting on the brain or modulating the gut-brain axis, ultimately to relieve Aβ1-42 -induced cognitive dysfunction.

Keyphrases

resting state
white matter
high glucose
diabetic rats
functional connectivity
induced apoptosis
cerebral ischemia
oxidative stress
drug induced
signaling pathway
cell cycle arrest
type diabetes
mouse model
adipose tissue
cell death
blood brain barrier
pi k akt