Magnetic Resonance Imaging Tissue Signatures Associated With White Matter Changes Due to Sporadic Cerebral Small Vessel Disease Indicate That White Matter Hyperintensities Can Regress.

Angela C C Jochems Susana Muñoz Maniega Una Clancy Carmen Arteaga ReyesDaniela Jaime GarciaFrancesca M Chappell Will Hewins Rachel Locherty Ellen V BackhouseGayle BarclayCharlotte JardineDonna McIntyreIona GerrishAgniete KampaiteEleni SakkaMaria Valdés HernándezStewart J Wiseman Mark E Bastin Michael S Stringer Michael Jonathan Thrippleton Fergus N Doubal Joanna Marguerite Wardlaw

Published in: Journal of the American Heart Association (2024)

Quantitative magnetic resonance imaging shows that WMHs that regress have less abnormal microstructure at baseline than stable WMHs and follow trajectories indicating tissue improvement compared with stable and progressing WMHs.

Keyphrases

white matter
magnetic resonance imaging
multiple sclerosis
computed tomography
contrast enhanced
depressive symptoms
subarachnoid hemorrhage
late onset
high resolution
genome wide
dna methylation
gene expression
diffusion weighted imaging
brain injury
cerebral ischemia
amyotrophic lateral sclerosis
early onset