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Assessing the Occurrence and Influence of Cancer Chemotherapy-Related Pharmacogenetic Alleles in the Chilean Population.

Gareth I OwenMiguel Córdova-DelgadoBernabe Ignacio BustosLeslie C CerpaPamela GonzalezSebastian MoralesBenjamín Garcia-BlojMarcelo GarridoJuan Francisco MiquelLuis Abel Quiñones
Published in: Pharmaceutics (2024)
This study provides the first comprehensive pharmacogenetic characterization of cancer therapy-related SNPs and highlights significant disparities in SNP frequencies within the Chilean population. Our findings underscore the necessity for inclusive research and personalized therapeutic strategies to ensure the equitable and effective application of precision medicine across diverse global communities.
Keyphrases
  • cancer therapy
  • genome wide
  • risk assessment
  • drug delivery
  • papillary thyroid
  • healthcare
  • squamous cell carcinoma
  • dna methylation
  • lymph node metastasis
  • drug induced
  • genome wide association