Assessing the Occurrence and Influence of Cancer Chemotherapy-Related Pharmacogenetic Alleles in the Chilean Population.
Gareth I OwenMiguel Córdova-DelgadoBernabe Ignacio BustosLeslie C CerpaPamela GonzalezSebastian MoralesBenjamín Garcia-BlojMarcelo GarridoJuan Francisco MiquelLuis Abel QuiñonesPublished in: Pharmaceutics (2024)
This study provides the first comprehensive pharmacogenetic characterization of cancer therapy-related SNPs and highlights significant disparities in SNP frequencies within the Chilean population. Our findings underscore the necessity for inclusive research and personalized therapeutic strategies to ensure the equitable and effective application of precision medicine across diverse global communities.