Validation of the EQ-5D-5L and psychosocial bolt-ons in a large cohort of people living with multiple sclerosis in Australia.

Julie A CampbellHasnat AhmadGang Chen Ingrid A van der Mei Bruce V TaylorSuzi ClaflinGlen James Henson Steve Simpson Yap Laura Louise LaslettKirsty HawkesCarol HurstHilary WaughAndrew J Palmer

Published in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2022)

The EQ-5D-5L-Psychosocial is more sensitive than the EQ-5D-5L in pwMS whose HSUs approach those reflecting full health. When respondent burden is taken into account, the EQ-5D-5L-Psychosocial is preferential to the AQoL-8D. We suggest a larger confirmatory study comparing all prevalent multi-attribute utility instruments for pwMS.

Keyphrases

mental health
multiple sclerosis
healthcare
public health
white matter
risk assessment
patient reported outcomes