New method to preserve the original proportion and integrity of urinary cell-free DNA.

Pei LiJun NingXipeng LuoHongli DuQing ZhangGanlin ZhouQiu DuZhenyu OuLong WangYu Wang

Published in: Journal of clinical laboratory analysis (2018)

Using UCTs, they can maximally keep the original proportion and integrity of ucfDNA and stabilize urinary cells and minimize the background noise caused by urinary cellular DNA releasing, it will be help to open the door of next-generation noninvasive liquid biopsy applications utilizing urine.

Keyphrases

induced apoptosis
circulating tumor
air pollution
cell free
ultrasound guided
oxidative stress
endoplasmic reticulum stress
signaling pathway
nucleic acid