Culture-Independent Analysis of Pediatric Bronchoalveolar Lavage Specimens.
Philip ZachariahChanelle RyanSruti NadimpalliGina CosciaMichelle KolbHannah SmithMarc FocaLisa SaimanPaul J PlanetPublished in: Annals of the American Thoracic Society (2019)
Culture-independent analysis was concordant with routine cultures and showed the potential to detect noncultured pathogens. Although culture-independent testing identified relative changes in organism abundance associated with clinical characteristics, distinct microbiome profiles associated with disease states were not identified.