Small Dense Low-Density Lipoprotein Cholesterol and Coronary Artery Calcification in the Multi-Ethnic Study of Atherosclerosis.
Rishi RikhiChristopher L SchaichGeorge W HafzallaNisha A PatelJordan E TannenbaumCharles A GermanTamar PolonskyMichael Y TsaiMuhammad I AhmadTareq IslamParag A ChevliMichael D ShapiroPublished in: European journal of preventive cardiology (2024)
In a large, multi-ethnic sample without known CVD, higher sd-LDL-C was associated with the presence of CAC, above and beyond total LDL-C. Whether selective direct measurement of sd-LDL-C is indicated to refine cardiovascular risk assessment in primary prevention warrants further investigation.