Polygenic liability for schizophrenia and childhood adversity influences daily-life emotion dysregulation and psychosis proneness.

Lotta-Katrin PriesB KlingenbergC Menne-LothmannJ DecosterR van WinkelD CollipP DelespaulJohan DetrauxC DeromE ThieryN JacobsM WichersOzan CinarB D LinJurjen J LuykxB P F RuttenJ van OsS Guloksuz

Published in: Acta psychiatrica Scandinavica (2020)

Exposure to childhood adversities, particularly in individuals with high PRS-S, is pleiotropically associated with emotion dysregulation and psychosis proneness.

Keyphrases

early life
autism spectrum disorder
depressive symptoms
bipolar disorder
childhood cancer
borderline personality disorder
physical activity
young adults