Antihypertensive and Vasorelaxant Effects of Citrus aurantifolia Linn. Fruit: Proposed Mechanisms.

Syed Nasir Abbas BukhariDr Alamgeer -Sumera SaeedMulazim Hussain AsimHafiz Muhammad IrfanHasan EjazMervat A ElsherifKashaf Junaid

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

fruit produced hypotensive and antihypertensive effects in rats. The extract elicited endothelium-independent vasorelaxation, possibly by acting directly on smooth muscles of the coronary artery and by increasing cGMP and cAMP via nonselective inhibition of vascular PDEs.

Keyphrases

coronary artery
blood pressure
nitric oxide
hypertensive patients
pulmonary artery
protein kinase
pulmonary hypertension