Combinatorial Synthesis of Indole Derivatives as Anti-oomycetes Agents.
Fei HaiRuxue WeiYan LiRuiguang WangYuee TianShengming LiuGenqiang ChenZhiping ChePublished in: Combinatorial chemistry & high throughput screening (2023)
The preliminary structure-activity relationship showed that the formyl group modification at the C-3 position of the indole ring was acceptable, and the different anti-oomycete activities of R1 and R2 were significantly different, with R1 being 5-CN > H > 6-Me, and R2 being 4-NO2 > 3-NO2, H > 4-Me.