Acute vs cumulative benefits of metformin use in patients with type 2 diabetes and heart failure.

Daniala L WeirMichal AbrahamowiczMarie-Eve BeauchampDean T Eurich

Published in: Diabetes, obesity & metabolism (2018)

Our results suggest that cumulative metformin exposure does not decrease the risk of HF-related exacerbation. Use of other anti-hyperglycaemic agents with proven efficacy in patients with HF should also be considered as treatment options in this population.

Keyphrases

acute heart failure
heart failure
respiratory failure
liver failure
chronic obstructive pulmonary disease
drug induced
left ventricular
aortic dissection
atrial fibrillation
intensive care unit
hepatitis b virus
mechanical ventilation