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Identification of differentially expressed Atlantic salmon miRNAs responding to salmonid alphavirus (SAV) infection.

Rune AndreassenNardos Tesfaye WoldemariamIne Østråt EgelandOleg AgafonovHilde SindreBjørn Høyheim
Published in: BMC genomics (2017)
This study represents the first steps in exploring miRNAs important in viral-host interaction in Atlantic salmon. We identified several miRNAs responding to SAV infection. Some likely to prohibit harmful inflammation while other may promote an early immune response. Their predicted functions need to be validated and further studied in functional assays to fully understand their roles in immune homeostasis.
Keyphrases
  • immune response
  • oxidative stress
  • sars cov
  • high throughput
  • dendritic cells
  • single cell