Sex differences in hearing impairment due to diet-induced obesity in CBA/Ca mice.

Soo Jeong KimAkanksha GajbhiyeAh-Ra LyuTae Hwan KimSun-Ae ShinHyuk Chan KwonYong-Ho ParkMin Jung Park

Published in: Biology of sex differences (2023)

Female mice are more resistant to the negative effects of an HFD on body weight, metabolism, and hearing. Females showed increased peripheral and intra-cochlear adiponectin and AdipoR1 levels, and HC ribbon synapses. These changes may mediate resistance to HFD-induced hearing loss seen in female mice.

Keyphrases

hearing loss
high fat diet induced
body weight
insulin resistance
high fat diet
metabolic syndrome
type diabetes
adipose tissue
weight gain
body mass index
wild type
physical activity
endothelial cells