Assessing the use of a micro-sampling device for measuring blood protein levels in healthy subjects and COVID-19 patients.
Joost BrandsmaJosh G ChenowethMelissa K GregorySubramaniam KrishnanPaul W BlairDeborah A StriegelRittal MehtaKevin L SchullyJ Stephen DumlerCdr Cynthia S SikorskiKelsey O'ConnorSusan A Reichert-ScrivnerCarmen M PaguiriganCatherine F T UyeharaCol Viseth NgauyChristopher A MyersDanielle V ClarkPublished in: PloS one (2022)
Self-collection of capillary blood with micro-sampling devices provides an attractive alternative to routine phlebotomy. However, concentrations of certain analytes may differ significantly from those in venous samples, and factors including user proficiency, temperature control and time lags between specimen collection and processing need to be considered for their effect on sample quality and reproducibility.