Orexin/Hypocretin Type 2 Receptor (HCRTR2) Gene as a Candidate Gene in Sertraline-Associated Insomnia in Depressed Patients.

Negar FirouzabadiNiloofar NavabzadehEbrahim Moghimi-SaraniMaral Haghnegahdar

Published in: Neuropsychiatric disease and treatment (2020)

In conclusion, the G1246A variant might be a predictor for insomnia in MDD patients treated with sertraline. Our findings support the idea that some variants of the HCRTR might contribute to inter-individual variability in the sleep pattern of patients receiving antidepressants.

Keyphrases

copy number
end stage renal disease
sleep quality
major depressive disorder
genome wide
newly diagnosed
chronic kidney disease
physical activity
dna methylation
bipolar disorder
genome wide analysis