Thymol protects against 6-hydroxydopamine-induced neurotoxicity in in vivo and in vitro model of Parkinson's disease via inhibiting oxidative stress.

Saeideh NourmohammadiSanaz YousefiMahboubeh ManouchehrabadiMona FarhadiZahra AziziAnahita Torkaman-Boutorabi

Published in: BMC complementary medicine and therapies (2022)

Collectively, our findings suggest that thymol exerts protective effects, possibly related to an anti-oxidation mechanism, in these in vitro and in vivo models of Parkinson's disease.

Keyphrases

oxidative stress
diabetic rats
high glucose
dna damage
hydrogen peroxide
nitric oxide
induced apoptosis
endothelial cells
heat shock