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Use of nalbuphine as a substitute for butorphanol in combination with dexmedetomidine and tiletamine/zolazepam: a randomized non-inferiority trial.

Rachael E KreislerHeather N CornellVeronica A SmithSamantha E KelseyErik H Hofmeister
Published in: Journal of feline medicine and surgery (2019)
The clinical experience of the nalbuphine-based combination was non-inferior to the butorphanol-based combination. Nalbuphine is an effective substitute for butorphanol, providing another option if butorphanol is unavailable due to shortage, controlled status or cost, without requiring a change in anesthetic workflow.
Keyphrases
  • clinical trial
  • cardiac surgery
  • phase iii
  • acute kidney injury
  • double blind