Risk-Factor Trajectories Preceding Diabetic Polyneuropathy: ADDITION-Denmark.

Signe Toft AndersenDaniel R WitteHenning AndersenLasse BjergNiels Henrik BruunMarit Eika JorgensenNanna B FinnerupTorsten LauritzenTroels S JensenHatice TankisiMorten Charles

Published in: Diabetes care (2018)

Both higher levels and slopes of HbA1c trajectories were associated with DPN after 13 years. Our findings indicate that the rate of HbA1c increase affects the development of DPN over and above the effect of the HbA1c level. Furthermore, this study supports obesity as a risk factor for DPN.

Keyphrases

type diabetes
depressive symptoms
risk factors
weight loss
weight gain
high fat diet induced
physical activity