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Review of the mechanism of action of coal tar in psoriasis.

Sahil SekhonCaleb JeonMio NakamuraLadan AfifiDi YanJashin J WuWilson LiaoTina Bhutani
Published in: The Journal of dermatological treatment (2017)
Polycyclic aryl hydrocarbons, and specifically carbazole, are thought to be the mechanism by which crude coal tar has its effect in psoriasis. However, further research is warranted to fully characterize the mechanism of action of crude coal tar, with the potential to create new therapies for psoriasis.
Keyphrases
  • particulate matter
  • heavy metals
  • atopic dermatitis
  • air pollution
  • risk assessment
  • human health
  • climate change