Association of common candidate variants with vascular malformations and intracranial hemorrhage in hereditary hemorrhagic telangiectasia.

Ludmila PawlikowskaJeffrey NelsonDiana E GuoCharles E McCullochMichael T LawtonHelen KimMarie E Faughnannull null

Published in: Molecular genetics & genomic medicine (2018)

We did not replicate previously reported associations with HHT lung AVM and variants in Tgfb modifier loci. We also did not find significant associations between variants reported in sporadic brain AVM and VM or ICH in HHT.

Keyphrases

copy number
genome wide
white matter
late onset
gene expression
dna methylation
multiple sclerosis
blood brain barrier
brain injury
subarachnoid hemorrhage