Plasma Metabolomics and Lipidomics Differentiate Obese Individuals by Peripheral Neuropathy Status.

Kai Guo Masha Georges Savelieff Amy E Rumora Fadhl M Al-Akwaa Brian Christopher Callaghan Junguk Hur Eva L Feldman

Published in: The Journal of clinical endocrinology and metabolism (2021)

Obesity may be as strong a PN driver as prediabetes or T2D in a sample of individuals with average class 3 obesity, at least by plasma metabolomics and lipidomics profile. Metabolic and complex lipid pathways can differentiate obese individuals with and without PN, independent of glycemic status.

Keyphrases

weight loss
metabolic syndrome
type diabetes
insulin resistance
adipose tissue
mass spectrometry
bariatric surgery
weight gain
high fat diet induced
obese patients
glycemic control
physical activity