Rare and common variants associated with alcohol consumption identify a conserved molecular network.
Brittany S LegerJohn J MeredithTrey IdekerSandra Sanchez-RoigeAbraham A PalmerPublished in: Alcohol, clinical & experimental research (2024)
Genes implicated by network colocalization identify shared biology relevant to alcohol consumption, which also underlie neuropsychiatric traits and substance use disorders that are comorbid with alcohol use, providing a more holistic understanding of two disparate sources of genetic information.