A case of successful surgical treatment of left ventricular thrombus associated with acute myocardial infarction by Impella combined with extracorporeal membrane oxygenation approach.
Rieko KutsuzawaNaoki TadokoroSatoshi KainumaNaonori KawamotoKouta SuzukiAyumi IkutaKohei TonaiMasaya HirayamaYoshiyuki TomishimaYasuhide AsaumiSatsuki FukushimaPublished in: Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs (2024)
The mortality rate in patients with heart failure complicated by cardiogenic shock following acute myocardial infarction (AMI) remains high, prompting research on mechanical circulatory support. Improved mortality rates have been reported with the early introduction of EcMELLA (Impella combined with extracorporeal membrane oxygenation, ECMO). However, clear indications for this treatment have not been established, given the associated risks and limitations related to access routes. Left ventricular thrombosis is traditionally considered a contraindication for Impella use. A 74-year-old man without specific medical history or coronary risk factors was diagnosed with Forrester IV heart failure due to cardiogenic shock complicated by AMI and left ventricular thrombosis. The patient underwent emergency coronary artery bypass surgery, intracardiac thrombus removal, and Dor surgery. Following cardiopulmonary bypass, ongoing heart failure was observed, necessitating the implementation of EcMELLA for circulatory support. Preoperative computed tomography showed that the bilateral subclavian arteries were too narrow (< 7 mm) and anatomically unsuitable for traditional access methods. Thus, we introduced a single-access EcMELLA 5.5, through which the Impella was introduced and veno-arterial-ECMO blood was delivered from a single artificial vessel anastomosed to the brachiocephalic artery. The patient was weaned off veno-arterial-ECMO and extubated on postoperative day 3. By postoperative day 14, improved cardiac function allowed for Impella removal. The patient was discharged on postoperative day 31 with improved ambulation; thereafter, the patient returned to work. Thus, the single-access EcMELLA5.5 treatment strategy combined with Dor procedure was effective in left ventricular thrombosis in patients with heart failure with cardiogenic shock complicated by AMI.
Keyphrases
- extracorporeal membrane oxygenation
- acute myocardial infarction
- left ventricular
- coronary artery bypass
- acute respiratory distress syndrome
- heart failure
- percutaneous coronary intervention
- cardiac resynchronization therapy
- respiratory failure
- case report
- risk factors
- hypertrophic cardiomyopathy
- minimally invasive
- patients undergoing
- aortic stenosis
- computed tomography
- mitral valve
- pulmonary embolism
- healthcare
- left atrial
- coronary artery disease
- emergency department
- mechanical ventilation
- cardiovascular events
- acute coronary syndrome
- public health
- primary care
- intensive care unit
- acute heart failure
- aortic valve
- quality improvement
- surgical site infection