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Neurosyphilis and the Jarisch-Herxheimer reaction: A therapy concern with HIV disease.

Rajendra KapilaRobert A Schwartz
Published in: Dermatologic therapy (2021)
Jarisch-Herxheimer reaction (JHR) should be anticipated in treating neurosyphilis with coexistent human immunodeficiency virus (HIV) encephalitis. In that context we have devised a staging classification for JHR. In addition, an illustrative case is provided to emphasize the need to consider the diagnosis of neurosyphilis in HIV patients, and if delineated, to be prepared for a severe JHR.
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