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Therapeutic effect of human ApoA-I-Milano variant in aged transgenic mouse model of Alzheimer's disease.

Montse SoléPaula MarazuelaLaura CastelloteAnna Bonaterra-PastraLydia Giménez-LlortMar Hernandez-Guillamon
Published in: British journal of pharmacology (2023)
Our study shows the potential therapeutic applicability of a safe and noninvasive treatment based on peripheral administration of hrApoA-I-M in AD.
Keyphrases
  • mouse model
  • endothelial cells
  • cognitive decline
  • mild cognitive impairment