Early-life famine exposure and risk of osteoporosis and low bone mineral density: a systematic review and meta-analysis.
Amirhossein Ghaseminejad-RaeiniAlireza AzarbooNegar ZareshahiSayeh JalaliParisa FallahtaftiAli HomaeiAmirhossein ShirinezhadAmir Human HoveidaeiPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2024)
Early-life famine exposure is significantly associated with an increased risk of osteoporosis, fractures, and lower BMD in later life. These results emphasize the lasting effects on bones from early lack of nutrition and stress the importance of specific interventions for bone health in groups with past famine experiences. Future studies should investigate the reasons behind these connections and assess preventative approaches to reduce the negative effects on bone health in those impacted.