Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions.
Guy Hajj-BoutrosAndréa FaustJohn MuscederePerry KimNaji AbumradStéphanie ChevalierMylene Aubertin-LeheudreHoward BergmanDawn BowdishJessica BurfordStacy Carrington-LawrenceHélène CôtéDavid E DawePhilipe de Souto BarretoColin FarrellyRobert FowlerGilles GouspillouLea HarringtonSofie LautrupSusan E HowlettMahdi ImaniJames KirklandGeorge KuchelFrédérick A MalletteJosé A MoraisJohn C NewmanDaryl PullmanFelipe SierraJeremy M Van RaamsdonkAreti-Angeliki VeronikiR Jane RylettGustavo DuquePublished in: The journals of gerontology. Series A, Biological sciences and medical sciences (2024)
The inaugural Canadian Conferences on Translational Geroscience were held as two complementary sessions in October and November 2023. The conferences explored the profound interplay between the biology of aging, social determinants of health, the potential societal impact of geroscience and the maintenance of health in aging individuals. Although topics such as cellular senescence, molecular and genetic determinants of aging and prevention of chronic disease were addressed, the conferences went on to emphasize practical applications for enhancing older people's quality of life. This manuscript summarizes the proceeding and underscores the synergy between clinical and fundamental studies. Future directions highlight national and global collaborations and the crucial integration of early-career investigators. This work charts a course for a national framework for continued innovation and advancement in translational geroscience in Canada.