Phase 1 pharmacokinetics and safety study of extended duration dapivirine vaginal rings in the United States.
Albert Y LiuClara Dominguez IslasHolly GundackerBlazej NeradilekCraig HoesleyAriane van der StratenCraig W HendrixMay BeamerCindy E JacobsonTara McClureTanya HarrellKatherine E BungeBrid DevlinJeremy NuttallPatrick SpenceJohn SteytlerJeanna M PiperMark A Marzinkenull nullPublished in: Journal of the International AIDS Society (2021)
The extended duration DPV rings were well-tolerated and achieved higher DPV concentrations compared with the monthly DPV ring. These findings support further evaluation of three-month DPV rings for HIV prevention.
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