The Identification of CELSR3 and Other Potential Cell Surface Targets in Neuroendocrine Prostate Cancer.
Lucie Van EmmenisSheng Yu KuKaitlyn M GayvertJonathan R BranchNicholas J BradySubhasree BasuMichael RussellJoanna CyrtaAram VosoughiVerena SailerHussein AlnajarEtienne DardenneElena KoumisLoredana PucaBrian D RobinsonMichael D FeldkampAnnmarie WinkisNathan MajewskiBrent RupnowMarco M GottardisOlivier ElementoMark A RubinHimisha BeltranDavid S RickmanPublished in: Cancer research communications (2023)
The development of effective treatment for patients with NEPC remains an unmet clinical need. We have identified specific surface proteins, including CELSR3, that may serve as novel biomarkers or therapeutic targets for NEPC.