Pulsatility of glucocorticoid hormones in pregnancy: Changes with gestation and obesity.

Laura I StirratJamie J WalkerKsenia StryjakowskaNatalie JonesNatalie Z M HomerRuth AndrewJane E NormanStafford L LightmanRebecca M Reynolds

Published in: Clinical endocrinology (2018)

We demonstrate cortisol pulsatility in interstitial fluid. Pulse frequency is altered with increased gestation and BMI. This may be a novel mechanism to explain decreased HPA activity in obese pregnancy.

Keyphrases

weight loss
preterm birth
metabolic syndrome
preterm infants
gestational age
type diabetes
pregnancy outcomes
weight gain
insulin resistance
adipose tissue
body mass index
blood pressure
bariatric surgery
high fat diet induced
skeletal muscle